Diagnosis of Large Granular Lymphocytic Leukemia in a Patient Previously Treated for Acute Myeloblastic Leukemia

نویسندگان

  • Sinem Civriz Bozdag
  • Sinem Namdaroglu
  • Omur Kayikci
  • Gülsah Kaygusuz
  • Itir Demiriz
  • Murat Cinarsoy
  • Emre Tekgunduz
  • Fevzi Altuntas
چکیده

Large granular lymphocytic (LGL) leukemia is a lymphoproliferative disease characterized by the clonal expansion of cytotoxic T or natural killer cells. We report on a patient diagnosed with T-cell LGL leukemia two years after the achievement of hematologic remission for acute myeloblastic leukemia.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Dysregulation of the WNT Signaling Pathway Through Methylation of Wnt Inhibitory Factor 1 and Dickkopf-1 Genes among AML Patients at the Time of Diagnosis

Background: In acute myeloblastic leukemia, a large number of tumor suppressor genes are silenced through DNA methylation such as CDKN2B & p73. Wnt inhibitory factor 1 (WIF1) and Dickkopf-3 (DKK-1) are negative regulators of Wnt signaling pathway. In the present study, we evaluated the methylation status of WIF1 and DKK-1 genes in acute myeloblastic leukemia patients. Patients and Methods: ...

متن کامل

Metronomic Maintenance Therapy in Refractory Acute Myeloblastic Leukemia with Monosomy 7

Patients with acute myeloblastic leukemia (AML) with monosomy 7 are a group of patients with refractory AML who have a very poor prognosis. Therefore, rationally designed new therapies, including metronomic chemotherapy regimen with histidine deacetylase inhibitors (Valporic acid, ATRA) are being investigated as potential treatments for the population of refractory cases of AML. Herein, we repo...

متن کامل

Antineoplastic Effect of Fenugreek (Trigonella Foenum Graecum) Seed Extract against Acute Myeloblastic Leukemia Cell Line (KG-1)

Background: Treatment of cancer patients using conventional chemotherapy causes serious side effects and, at best, merely extends the patient’s lifespan by a few years. The potential of alternative therapies may therefore be of great benefit in cancer control. The effect of Trigonella Foenum Graecum seed extract has been previously reported on some neoplastic cells. Here, its effect is evaluate...

متن کامل

A Fuzzy Expert System for Diagnosis of Acute Lymphocytic Leukemia in Children

Fuzzy expert systems are one of the most practical intelligent models with the high potential for managing uncertainty associated to the medical diagnosis. In this paper, a fuzzy inference system (FIS) for diagnosing of acute lymphocytic leukemia in children has been introduced. The fuzzy expert system applies Mamdani reasoning model that has high interpretability to explain system results to e...

متن کامل

A Fuzzy Expert System for Diagnosis of Acute Lymphocytic Leukemia in Children

Fuzzy expert systems are one of the most practical intelligent models with the high potential for managing uncertainty associated to the medical diagnosis. In this paper, a fuzzy inference system (FIS) for diagnosing of acute lymphocytic leukemia in children has been introduced. The fuzzy expert system applies Mamdani reasoning model that has high interpretability to explain system results to e...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2013